Mfb10 specifications production capacity 2 to 20 kilos air flow capacity 2,000 m3hr, maximum fan power electrical heater 4 kw 12 kw optional rotor disc power 1. Fluidized bed dryer fbd is well known and widely used equipment in granulation area of pharmaceutical manufacturing. Tangential spray fluid bed granulation the second fluid bed technique for wet granulation is the tangentialspray rotary process, available since the early 1980s fig. The rotating disk is located at the base of the product container. Among many types of surface modification or composite formation processes, fluid bed processes are characterized. Conclusion fluid bed processor offer unique opportunity to develop coated controlled release products. How to optimize fluid bed processing technology 1st edition. With a multifunction capability, every fluid bed dryer can integrate top spray granulating, bottom spray coating and tangent spray pelleting or coating.
Pdf following a brief overview of recent developments in laundry powder processing by comparison with other areas of industrial application, and. The fluid bed rotor processor utilizes a rotating disk and fluidization air. At the fluidizing velocity, solid particles are dispersed and surrounded by gas. World wide in pharmaceutical industry, fluid bed processing technology emerged as useful application. Today, about threequarters of all polyolefins are made by a fluidized bed process. Obtaining this process analytical technology pat measurement in real time allows for continu. Introduction to fluid bed processing the principle of a fluid bed is to maintain particles in suspension in a close area by blowing air through the particle bed. Multiple distributor plates and internal component options provide. Fbe series is a worldclass range of fluid bed processors from acg pharma technologies. Offering high spray rates for short processes, nonpareil starter pellets are sprayed with a solution or suspension of the active material and dried simultaneously. Reduced building envelope in both height and footprint. Fluid bed machines come in a wide range of designs and configurations that suit various applications in the pharmaceutical industry.
In fluid bed cooling, cold gas air is used to remove heat. In many cases, the fluid bed processors from saintyco are multifunction as you can use them for different purposes. It is used in the granulation process for drying the material to get desired moisture content in the tablet formulation granules required for perfect compression of tablets. Fluid bed processing passes a gas directly through a bed of solid material via a perforated plate, nozzles, ceramic grid or other fluidizing media, lifting and mixing the solids. Controlled particle flow coating partition coating spray in contrast. By raising the disk, a gap around the edge of the disk is formed. Fluid bed processing involves drying, agglomeration, granulation, and coating of particulate materials.
Principle of the fluid bed dryer the air stream, induced by the fan 2 in the upper part of the cabinet, passes through the air heater 7 and the prefilter 9. A comparison of granules produced by highshear and fluidized. Offering high spray rates for short processes, nonpareil starter pellets are sprayed with a solution or suspension of. Thus, the particles remain dry through the entire process. Fluid bed processor is a very good technology to make granules from powder using top spray method. It is important to investigate and understand these variables to ensure a reproducible performance of controlled release products. The bepex fluid bed system provides a finishing step along with one of our other processing technologies engineered for thermal treatment of heatsensitive and fragile feed materials.
The nozzle is a binary type one port of nozzle for liquid while other for atomized air at predecided volume and pressure. Fluid bed processing fluid bed granulation and wurster coating in dry stage granulation, the. Figure 4b shows the cross section, which reveals the interstitial void space. Aug 27, 2016 conclusion fluid bed processor offer unique opportunity to develop coated controlled release products. Product brochures and other files available for download. For instance, you may need a fluid bed processor that can granulate, coat and dry the particles at the same time. Tangential spray fluid bed granulation the second fluidbed technique for wet granulation is the tangentialspray rotary process, available since the early 1980s fig. Fluidizes bed processor mini glatt, a component laboratory device uses the above principle and the equipment is designed to perform drying, granulation. Gea supplies fluid bed processors known as fluid bed multiprocessor in the usa for blending, granulating, drying, pelletizing and coating for the. Moreover, the fluid bed agglomeration process is a combination of three steps. Wet powder mixing, drying, milling, grading and blending.
Domed top cover, top end feed, bottom end discharge. The granules are then usually transferred to another piece of equipment for drying, such as a fluidizedbed dryer. It is ideal for a wide range of both heat sensitive and nonheat sensitive products. The granulating solution is applied at a rate less than or equal to its evaporation rate. Fbc fluidized bed coater, fbd fluidized bed dryer, fbg fluidized bed granulator. Simpletouse, economical, and designed for maximum processing effectiveness, the vfc flocoater family is the ideal solution for your current and future fluid bed processing requirements. It is ideal equipment that is in conformity with the requirements of cgmp. A definitive guide to fluid bed granulation process updated. All airflow through the processing chamber passes through this gap. The state of the bed depends thereby on the air velocity and on the particle properties. The spray pattern is in a solid cone of droplets, with a spray angle approximately 3050 called as coating zone.
Please register before downloading the pdf files glatt provides. It is ideal for heat sensitive and non heat sensitive products in pharmaceuticals, chemicals and biochemical, food and dairy industries. Quality risk management of top spray fluidized bed process for. The edge of the disk sits against the wall of the product container. Fluid bed processor for pharmaceuticals authorstream. Fluid air fluid bed systems are designed to maintain critical scaleup factors from one unit to the next. An external file that holds a picture, illustration, etc.
Click the link to view an interactive pdf with the following data for 53992 topspray granulating lance u. Fluidbed processor and granulator manufacturer saintyco. Innovations in pharmacy and pharmaceutical technology. Saintyco fluid bed dryer is a highly efficient cgmp compliant machine designed to uniformly and effectively dry powder and granules. Fluid bed wurster beadcoating, layering and encapsulation. Fluidizes bed processor mini glatt, a component laboratory device uses the above principle and the equipment is designed to perform drying, granulation and coating wurster process, after a few. Processes ranging from powdery materials to freeflowing materials can be carried out as well as the drying of moist products e. Mfb1 specifications production capacity 100 grams to 1 kilo air flow capacity 145 ft3min fan power 1. Starting with our model 50, to our largest available units, each system operates with nearly identical bed depths, air velocities, and air ratios quantity of air per cubic foot of product, greatly simplifying the scale up of product from one unit to the next. Mfb1 specifications production capacity 100 grams to 1 kilo air.
Flgurc 2b shows a crosssection, which reveals the interstillal void space. Part of the expertise in pharmaceutical process technology series addresses the important components of fluid bed granulation, providing answers to problems that commonly arise and using numerous practical examples and case studies as reference this book covers the theoretical concepts involved in fluidization. However, one distinct feature is always the exact location of the spray system. Oil and paint color dye homogenizing mixing by colloid mill and stirrer. Optionally, the inlet air system may dry or humidify the air to a consistent dewpoint level. The midilab is the next larger laboratory fluid bed processor after the minilab, offering an increased range of applications. Click the link to view an interactive pdf with the following data for 53992 topspray granulating. Fluid bed wurster beadcoating, layering and encapsulation alkermes contract pharma services, a division of alkermes pharma ireland ltd, has significant experience in beadcoating processes to provide you with expert solutions to fulfill your specific manufacturing needs. Diosna midilab interchangeable bowl fluid bed processor for research and development. This is one of the main reasons why as fluid bed equipment manufacturers, we insist on installing intelligent control systems that can monitor all fluid bed. A single product container for all unit operations.
Fluid bed topspray granulation, blending, tableting and coating fluid bed processor glatt gpcg 300 tablet presses fette p2100 29 station tablet coaters blenders 120 or 300 topspray inserts 525l or 1,275l capacity automated recipe control system manual andor vacuum product loading. Fluid bed heat exchange takes place by passing a gas most commonly air through a perforated distributor plate which then flows through a layer bed of solids. The characteristics of fluid bed granulation processing and the fundamentals of the mechanisms contributing to wet granule growth are briefly discussed. Multizone design allows for extended processing flexibility, including heating and cooling in the same unit. The links to the pdf brochure files will be sent to the email. These are fluid bed processors that can perform more than one function.
The cld measurement is a function of particle size, particle shape, and particle population. Used carman industries vibrating fluid bed processor, model fbp340, carbon steel. We are the leading fluid bed granulation, fluid bed processor, fluid bed granulator, fluid bed coating, fluidized bed coating, and fluidized bed granulator. Fluid bed processor have been use for drying,agglomeration,and coating. Fluidized bed technology at its best allgaier process technology. Fluidbed spraydrying also offers lower operating costs and shorter process limes compared with freezedrying. Oct, 2015 fbe series is a worldclass range of fluid bed processors from acg pharma technologies. Prism fluid bed processing involves fast drying, cooling and agglomeration of particulate materials. Feb 07, 2016 fluid bed processing involves drying, agglomeration, granulation, and coating of particulate materials. Pdf validation of fluidized bed processor mini glatt. How fluid bed technology works for cooling, heating and.
Fluid bed processors gea engineering for a better world. Fluid bed processor fluid bed processor bottom spray. Click here to download a brochure in pdf format outlining glatts products and. Batch type fluid processes are using in pharmaceutical industry since 30 years. Battery, ceramics, carbide, silica and catalyst dry powder mixing, blending, milling and grading. Fluid bed topspray granulation, blending, tableting and. Fluid bed processing fluid bed granulation and wurster coating in dry stage granulation, the particles only require a slight wetting to become tacky and stick to each other.
But various process parameters can alter the performance of a product and hence should be examined thoroughly. The v2 variable vector technology allows you to quickly. Fluid bed granulation process parameters that may affect quality of granules as i said earlier, the ability to monitor various process parameters will ensure you get high quality granules. Fbd bags are fingerlike in structure to increase the surface area of the drying bed that helps to increase the drying rate and decrease the drying time during the fluidized bed drying process. Used carman industries vibrating fluid bed processor, model fbp340. Further more, the air inlet and exhaust air components can be built.
Fluid bed dryer fluid bed processor comes with range of capacities as per our customers requirement. For more than 50 years, gea has supplied fluid bed processors for blending, granulating, drying, pelletizing and coating for the pharmaceutical industry. In addition to a simple fluid bed, the tumbling, agitating, centrifugal, and spiral flow fluid bed and the spouted bed with or without draft tube have been developed for improving process perfomance. Ind estate ltd, charkop, kandivili west mumbai 400067. Originating in europe, this technology gradually found its way into u. Fluid beds typically operate under vacuum and have an inlet air handling system to condition the air to a given temperature and filtration level. Fluid bed systems hdhdghdgc drying, granulating, coating. General kinematics v2 variable vector fluid bed processor drive brings material processing to the next level. The excellent heat transfer and water evaporation rates reduce the dryer size to a minimum. An acetaminophen granule produced bv a conventional topspray fluid bed processor, at a magnification of60x. Fluid bed coating of powders, granules, or tablets involves the spraying of a liquid on the fluidized powder under strictly controlled conditions. Among many types of surface modification or composite formation processes.
Operating instructions fluid bed dryer bid on equipment. With more than 40 years of experience manufacturing for global markets at our. Processing equipment equipment processing inserts recommended working volume max wv gpcg 1 3. The development of a specialized zeolite catalyst for cracking heavy oil into various fractions enabled the commercialization of the fcc circulating fluidized bed. Mfb10 specifications production capacity 2 to 20 kilos air flow capacity 2,000 m3hr, maximum fan power electrical heater 4 kw. Depending on the application or position of their spray system, you may classify the available fluid bed equipment as. Part of the expertise in pharmaceutical process technology series addresses the important components of fluid bed granulation, providing answers to problems that commonly arise and using numerous practical examples and case studies as reference.
1355 1439 133 1284 1049 739 599 1048 1003 471 1378 1416 811 378 210 1146 65 163 936 1245 298 1237 1031 1420 837 209 819 1438 1369